Publications

Dr. Srivastava has published 189 research articles, mostly on human parvoviruses, in peer-reviewed journals, reviews, and book chapters. Selected publications are listed below.

• Srivastava A, Weitzman M, Chatterjee S, et al. A Tribute to Barrie J. Carter. Hum Gene Ther. 2020;31(9-10):491‐493. doi:10.1089/hum.2020.29118.bca
• Ran G, Chen X, Xie Y, et al. Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors. Mol Ther Methods Clin Dev. 2020;17:545‐555. Published 2020 Mar 13. doi:10.1016/j.omtm.2020.03.007
• Kwon HJ, Qing K, Ponnazhagan S, et al. Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Vectors for Modulating Humoral Immune Response. Hum Gene Ther. 2020;31(9-10):565‐574. doi:10.1089/hum.2020.018
• Berns KI, Srivastava A. Next Generation of Adeno-Associated Virus Vectors for Gene Therapy for Human Liver Diseases. Gastroenterol Clin North Am. 2019;48(2):319‐330. doi:10.1016/j.gtc.2019.02.005
• Agbandje-McKenna M, Srivastava A. XVIIth International Parvovirus Workshop. Hum Gene Ther. 2019;30(3):252‐256. doi:10.1089/hum.2019.29084.mam
• Büning H, Srivastava A. Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors. Mol Ther Methods Clin Dev. 2019;12:248‐265. Published 2019 Jan 26. doi:10.1016/j.omtm.2019.01.008
• Feng Y, Yin Z, Zhang D, Srivastava A, Ling C. Chinese Medicine Protein and Peptide in Gene and Cell Therapy. Curr Protein Pept Sci. 2019;20(3):251‐264. doi:10.2174/1389203719666180612082432
• Chen M, Maeng K, Nawab A, et al. Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors. Hum Gene Ther Methods. 2017;28(1):49‐59. doi:10.1089/hgtb.2016.089
• Markusic DM, Nichols TC, Merricks EP, et al. Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models. J Transl Med. 2017;15(1):94. Published 2017 May 1. doi:10.1186/s12967-017-1200-1
• Rogers GL, Shirley JL, Zolotukhin I, et al. Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8⁺ T cells. Blood. 2017;129(24):3184‐3195. doi:10.1182/blood-2016-11-751040
• Li M, Tang Y, Wu L, et al. The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation. Blood. 2017;130(8):1041‐1051. doi:10.1182/blood-2016-12-755967
• Srivastava A. Advances and challenges in the use of recombinant AAV vectors for human gene therapy. Cell and Gene Therapy Insights. 2016;2(5):553-575. doi:10.18609/cgti.2016.061
• Srivastava A, Carter BJ. AAV Infection: Protection from Cancer. Hum Gene Ther. 2017;28(4):323‐327. doi:10.1089/hum.2016.147
• Srivastava A. Adeno-Associated Virus: The Naturally Occurring Virus Versus the Recombinant Vector. Hum Gene Ther. 2016;27(1):1‐6. doi:10.1089/hum.2015.29017.asr
• Ling C, Bhukhai K, Yin Z, et al. High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing. Sci Rep. 2016;6:35495. Published 2016 Oct 19. doi:10.1038/srep35495
• Srivastava A. In vivo tissue-tropism of adeno-associated viral vectors. Curr Opin Virol. 2016;21:75‐80. doi:10.1016/j.coviro.2016.08.003
• Ling C, Li B, Ma W, Srivastava A. Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses. Hum Gene Ther Methods. 2016;27(4):143‐149. doi:10.1089/hgtb.2016.054
• Ling C, Yin Z, Li J, Zhang D, Aslanidi G, Srivastava A. Strategies to generate high-titer, high-potency recombinant AAV3 serotype vectors. Mol Ther Methods Clin Dev. 2016;3:16029. Published 2016 May 4. doi:10.1038/mtm.2016.29
• Vercauteren K, Hoffman BE, Zolotukhin I, et al. Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid. Mol Ther. 2016;24(6):1042‐1049. doi:10.1038/mt.2016.61
• Li B, Ma W, Ling C, et al. Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo. Hum Gene Ther Methods. 2015;26(6):211‐220. doi:10.1089/hgtb.2015.115
• Li S, Ling C, Zhong L, et al. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. Mol Ther. 2015;23(12):1867‐1876. doi:10.1038/mt.2015.174
• Ling C, Wang Y, Lu Y, et al. The Adeno-Associated Virus Genome Packaging Puzzle. J Mol Genet Med. 2015;9(3):175. doi:10.4172/1747-0862.1000175
• Ling C, Wang Y, Feng YL, et al. Prevalence of neutralizing antibodies against liver-tropic adeno-associated virus serotype vectors in 100 healthy Chinese and its potential relation to body constitutions. J Integr Med. 2015;13(5):341‐346. doi:10.1016/S2095-4964(15)60200-X
• Wang L, Yin Z, Wang Y, et al. Productive life cycle of adeno-associated virus serotype 2 in the complete absence of a conventional polyadenylation signal. J Gen Virol. 2015;96(9):2780‐2787. doi:10.1099/jgv.0.000229
• Ling C, Wang Y, Lu Y, et al. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo. J Virol. 2015;89(2):952‐961. doi:10.1128/JVI.02581-14
• Zhang YH, Wang Y, Yusufali AH, et al. Cytotoxic genes from traditional Chinese medicine inhibit tumor growth both in vitro and in vivo. J Integr Med. 2014;12(6):483‐494. doi:10.1016/s2095-4964(14)60057-1
• Ling C, Wang Y, Zhang Y, et al. Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model. Hum Gene Ther. 2014;25(12):1023‐1034. doi:10.1089/hum.2014.099
• Chen MJ, Lu Y, Hamazaki T, et al. Reprogramming adipose tissue-derived mesenchymal stem cells into pluripotent stem cells by a mutant adeno-associated viral vector. Hum Gene Ther Methods. 2014;25(1):72‐82. doi:10.1089/hgtb.2013.011
• Wang LN, Wang Y, Lu Y, et al. Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo. J Integr Med. 2014;12(1):20‐34. doi:10.1016/S2095-4964(14)60003-0
• Song L, Kauss MA, Kopin E, et al. Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo. Cytotherapy. 2013;15(8):986‐998. doi:10.1016/j.jcyt.2013.04.003
• Song L, Li X, Jayandharan GR, et al. High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo. PLoS One. 2013;8(3):e58757. doi:10.1371/journal.pone.0058757
• Song L, Kauss MA, Kopin E, et al. Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo. Cytotherapy. 2013;15(8):986‐998. doi:10.1016/j.jcyt.2013.04.003
• Aslanidi GV, Rivers AE, Ortiz L, et al. Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?. PLoS One. 2013;8(3):e59142. doi:10.1371/journal.pone.0059142
• Jayandharan GR, Aslanidi G, Martino AT, et al. Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy [retracted in: Proc Natl Acad Sci U S A. 2017 Dec 26;:]. Proc Natl Acad Sci U S A. 2011;108(9):3743‐3748. doi:10.1073/pnas.1012753108
• Zhong L, Li B, Mah CS, et al. Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses [published correction appears in Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):11032]. Proc Natl Acad Sci U S A. 2008;105(22):7827‐7832. doi:10.1073/pnas.0802866105
• Weigel-Kelley KA, Yoder MC, Srivastava A. Alpha5beta1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of beta1 integrin for viral entry. Blood. 2003;102(12):3927‐3933. doi:10.1182/blood-2003-05-1522
• Qing K, Mah C, Hansen J, Zhou S, Dwarki V, Srivastava A. Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat Med. 1999;5(1):71‐77. doi:10.1038/4758