Keyun Qing,
Biological Scientist IV
Department:
MD-PEDS-CELL / MOLEC THERP DIV
Business Phone:
(352) 273-8257
Business Email:
keyun.qing@ufl.edu
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-2740-1600
Publications
2023
Development of capsid- and genome-modified optimized AAVrh74 vectors for muscle gene therapy.
Molecular therapy. Methods & clinical development.
31
[DOI] 10.1016/j.omtm.2023.101147.
[PMID] 38046199.
2022
Development of an AAV DNA-based synthetic vector for the potential gene therapy of hemophilia in children.
Frontiers in microbiology.
13
[DOI] 10.3389/fmicb.2022.1033615.
[PMID] 36274690.
2021
AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo.
Gene therapy.
28(7-8):422-434
[DOI] 10.1038/s41434-020-0140-1.
[PMID] 32152434.
2021
Reply to “D” matters in recombinant AAV packaging.
Molecular therapy : the journal of the American Society of Gene Therapy.
29(9):2628-2630
[DOI] 10.1016/j.ymthe.2021.08.012.
[PMID] 34437839.
2020
Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Vectors for Modulating Humoral Immune Response.
Human gene therapy.
31(9-10):565-574
[DOI] 10.1089/hum.2020.018.
[PMID] 32220217.
2020
Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing.
Molecular therapy. Nucleic acids.
20:451-458
[DOI] 10.1016/j.omtn.2020.03.009.
[PMID] 32276210.
2020
Role of Essential Metal Ions in AAV Vector-Mediated Transduction.
Molecular therapy. Methods & clinical development.
18:159-166
[DOI] 10.1016/j.omtm.2020.05.019.
[PMID] 32637447.
2008
Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction.
Molecular therapy : the journal of the American Society of Gene Therapy.
16(2):290-5
[PMID] 18087261.
2007
Central CART gene delivery by recombinant AAV vector attenuates body weight gain in diet-induced-obese rats.
Regulatory peptides.
140(1-2):21-6
[PMID] 17182122.
2006
Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5.
Human gene therapy.
17(3):321-33
[PMID] 16544981.
2006
Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectors.
Virology.
353(2):283-93
[PMID] 16828834.
2004
Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90.
The Journal of biological chemistry.
279(13):12714-23
[PMID] 14711833.
2004
Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells.
Human gene therapy.
15(12):1207-18
[PMID] 15684697.
2004
Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy.
10(5):950-7
[PMID] 15509512.
2003
Adeno-associated virus type 2-mediated gene transfer: role of cellular T-cell protein tyrosine phosphatase in transgene expression in established cell lines in vitro and transgenic mice in vivo.
Journal of virology.
77(4):2741-6
[PMID] 12552015.
Grants
Jan 2023
ACTIVE
Development of optimized AAVrh74 vectors for gene therapy of muscular dystrophies
Role: Other
Funding: NATL INST OF HLTH NIAMS
Contact Details
Phones:
- Business:
- (352) 273-8257
Emails:
- Business:
- keyun.qing@ufl.edu
Addresses:
- Business Mailing:
-
CGRC, ROOM 490 B
PO BOX 100296
2033 MOWRY ROAD
GAINESVILLE FL 326100296 - Business Street:
-
2033 Mowry Road
Gainesville FL 32610